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目的：探讨Ｃ反应蛋白（ＣＲＰ）、红细胞沉降率（ＥＳＲ）在临床诊断感染性肾积水和肾积脓中的意义。方法：对临床确诊的２２例感染性肾积水患者和３１例感染性肾积脓患者及２０例正常对照者分别用ＥＬＩＳＡ法和魏氏法测定其血液ＣＲＰ和ＥＳＲ。结果：与正常对照组比较，感染性肾积水组的ＣＲＰ和ＥＳＲ明显升高，差异显著（Ｐ＜０．０５）；感染性肾积脓组的ＣＲＰ和ＥＳＲ升高更为明显（Ｐ＜０．０１）。结论：将ＣＲＰ≥３０ｍｇ／Ｌ、ＥＳＲ≥１００ｍｍ／１ｈ做为临界值，对临床诊断感染性肾积水和肾积脓有一定意义，并且ＣＲＰ的水平变化与临床表现相关（相关系数ｒ＝０．４１９，Ｐ＝０．００１）。
Objective: To investigate the significance of C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) in the diagnosis of infective hydronephrosis and pyometra. Methods: Blood CRP and ESR were measured by ELISA and Wilcoxon in 22 clinically diagnosed patients with infectious hydronephrosis, 31 patients with infectious pyogenic pneumonia and 20 normal controls. Results: Compared with the normal control group, the CRP and ESR in the infective hydronephrosis group were significantly increased (P <0.05), but the elevated CRP and ESR in the infective pyknosis group were more obvious (P < 0.01). CONCLUSIONS: Using CRP≥30mg / L and ESR≥100mm / lh as the cut-off value is of clinical significance for the diagnosis of infective hydronephrosis and pyometra, and the level of CRP is correlated with clinical manifestations (r = 0 .419, P = 0.001).