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目的:了解患缺氧缺血性脑病新生儿的基本情况和治疗效果,并分析其影响因素。方法:以2007年1月～2011年12月我院符合HIE诊断标准的新生儿为研究对象,收集患儿与其母亲的相关资料并对其治疗效果进行评定,应用Epidata双核双录法建立数据库后导入SPSS13.0进行统计分析。结果:①所调查的98例HIE患儿中,男64例,女34例,年龄6h～32天,平均胎龄(37.9±2.3)周,1 min Apgar评分低于7分者占61.2%,5 min Ap-gar评分低于7分者占51.0%,头颅CT诊断显示,轻度HIE患儿33例(33.7%),中度60例(61.2%),重度5例(5.1%),经常规治疗后,“治愈”25例(25.5%),“好转”58例(59.2%),“未愈”10例(10.2%),“死亡”5例(5.1%);②经单因素和多因素Logistic分析结果表明,有7个因素与HIE患儿的治疗效果有关,其中产程正常、脐带正常、胎盘正常、羊水正常的HIE患儿治疗效果较好,5分钟Apgar评分越低,患儿的治疗效果越差,CT诊断分度越轻,患儿的治疗效果越好,24小时以内入院对HIE患儿的治疗效果具有保护作用。结论:应加强孕母的围产期保健工作,重视胎儿监护,提高科室诊治水平,对新生儿HIE做到早发现、早诊断、早治疗,以改善HIE患儿的治疗效果。
Objective: To understand the basic situation of newborns with hypoxic-ischemic encephalopathy and the therapeutic effect, and analyze the influencing factors. Methods: From January 2007 to December 2011, neonates who meet the diagnostic criteria of HIE in our hospital were selected as the research objects. Relevant data of children and their mothers were collected and their therapeutic effects were evaluated. After the database was established by using Epidata binuclear dual-recording method Import SPSS13.0 for statistical analysis. Results: ①In 98 cases of HIE, 64 males and 34 females, ranging in age from 6h to 32 days with an average gestational age of 37.9 ± 2.3 weeks, had an Apgar score of less than 7 at 1 minute, accounting for 61.2% In 5 min Ap-gar score 51.0%, cranial CT diagnosis showed 33 (33.7%) mild HIE, 60 moderately (61.2%) moderate and 5 severe (5.1% After conventional treatment, 25 cases (25.5%) were cured, 59 cases were improved (59.2%), 10 cases were unhealed (10.2%) and 5 cases were death %). (2) Logistic analysis showed that there were 7 factors related to the therapeutic effect in children with HIE. The treatment of HIE children with normal umbilical cord, normal umbilical cord, normal amniotic fluid, and 5 The lower the Apgar score, the poorer the treatment effect in children. The lighter the diagnosis of CT, the better the treatment effect in children. The hospitalization within 24 hours has a protective effect on the treatment effect of HIE children. Conclusion: The perinatal care of pregnant women should be strengthened, the fetus guardianship should be emphasized, the department diagnosis and treatment level should be improved, early detection, early diagnosis and early treatment of neonatal HIE should be improved to improve the therapeutic effect of HIE.