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目的:探讨小肠原发性间变性大细胞淋巴瘤(ALCL)的组织学特点及免疫组化特征。方法:运用组织形态、免疫组化方法研究1例发生在小肠的间变性大细胞淋巴瘤并结合文献进行讨论。结果:间变性大细胞淋巴瘤其形态学表现为多样性。免疫组化CD30+,另外CD45RO+,CK,EMA也可阳性。结论:间变性大细胞淋巴瘤发生在小肠非常罕见。其形态学和免疫表型有一定的特殊性,并且预后良好,要与其他类型淋巴瘤,霍奇金淋巴瘤,恶性黑色素瘤,低分化腺癌鉴别。
Objective: To investigate the histological features and immunohistochemical features of primary anaplastic large cell lymphoma (ALCL) of the small intestine. METHODS: One case of anaplastic large cell lymphoma that developed in the small intestine was studied using histomorphometry and immunohistochemistry and was discussed in the literature. RESULTS: The morphological manifestations of anaplastic large cell lymphoma were diverse. Immunohistochemically, CD30+, CD45RO+, CK, and EMA can also be positive. CONCLUSIONS: Anaplastic large cell lymphomas are rare in the small intestine. Its morphological and immunophenotypic characteristics have certain specificity and a good prognosis. It should be differentiated from other types of lymphoma, Hodgkin’s lymphoma, malignant melanoma, and poorly differentiated adenocarcinoma.