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局部晚期或内科原因不能手术的非小细胞肺癌(NSCLC),放疗被认为是标准治疗,但常规放疗(60Gy)的预后不良、2年生存少于15%,失败的主要原因为局部控制不良及高的早期远处转移率。放疗剂量高于60Gy可改善局部控制,但远处微转移灶的控制需有效的全身治疗。 作者报道了1989年7月~1991年7月92例因医学或技术不能切除的NSCLC,除7例未作化疗
In patients with non-small cell lung cancer (NSCLC) that are locally advanced or medically inoperable, radiotherapy is considered standard therapy, but conventional radiotherapy (60 Gy) has a poor prognosis, with 2 years survival less than 15%. The main causes of failure are local control and High rate of early distant metastasis. Radiotherapy doses higher than 60 Gy can improve local control, but the control of distant micrometastases requires effective systemic treatment. The authors reported 92 cases of NSCLC that could not be resected due to medical or technique from July 1989 to July 1991, except 7 cases who did not undergo chemotherapy