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目的:评价含5%硝酸钾牙膏减轻牙本质敏感症状的临床效果。方法:根据随机、双盲、平行设计的试验原则,将63名受试者随机分为试验组(含5%硝酸钾牙膏)和对照组(普通牙膏)进行试验,试验周期为4周。采用视觉模拟疼痛评分法(VAS)分别记录基线和4周后受试牙的牙敏感指数。采用SPSS13.0软件包对数据进行非参数检验。结果:使用牙膏4周后,试验组牙本质敏感VAS值显著低于基线(P<0.05)。与对照组相比,试验组使用牙膏前后牙本质敏感VAS记分之差显著高于对照组(P<0.05)。结论:含5%硝酸钾牙膏具有显著的抗牙本质敏感效果,可改善患者的整体舒适度。
OBJECTIVE: To evaluate the clinical efficacy of 5% potassium nitrate toothpaste in alleviating the symptoms of dentin hypersensitivity. Methods: According to randomized, double-blind and parallel design principles, 63 subjects were randomly divided into test group (containing 5% potassium nitrate toothpaste) and control group (ordinary toothpaste) for 4 weeks. Visual acuity pain score (VAS) was used to record the tooth sensitivity index of the test teeth at baseline and after 4 weeks respectively. Using SPSS13.0 software package for data non-parametric test. RESULTS: After 4 weeks of toothpaste, the dentine-sensitive VAS values of the experimental group were significantly lower than those of the baseline (P <0.05). Compared with the control group, the dentin-sensitive VAS scores in the experimental group before and after using toothpaste were significantly higher than those in the control group (P <0.05). Conclusion: 5% potassium nitrate toothpaste has significant anti-dentin sensitivities and improves overall patient comfort.