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目的:分析新辅助化疗联合腹腔镜手术治疗结直肠癌的临床疗效。方法:将我院收治的48例结直肠癌患者随机分为观察组24例和对照组24例。对照组患者行单纯的腹腔镜手术治疗,观察组患者行新辅助化疗联合腹腔镜手术治疗。评价2组患者治疗后的体力状况和功能状态,同时随访观察并统计2组患者3年内的生存率。结果:观察组患者治疗后的平均PS评分低于对照组(P<0.05),平均KPS评分高于对照组(P<0.05)。观察组患者3年内生存率为58.33%,对照组为37.5%,观察组患者3年内的生存率高于对照组(P<0.05)。结论:相较于单纯的腹腔镜手术,新辅助化疗联合手术治疗结直肠癌的临床疗效更为显著,能有效提高患者的体力状况,改善功能状态,并提高患者3年内的生存率,值得临床推广与应用。
Objective: To analyze the clinical effect of neoadjuvant chemotherapy combined with laparoscopy in the treatment of colorectal cancer. Methods: Forty-eight patients with colorectal cancer admitted to our hospital were randomly divided into observation group (24 cases) and control group (24 cases). Patients in the control group underwent simple laparoscopic surgery and patients in the observation group underwent neoadjuvant chemotherapy combined with laparoscopic surgery. The physical status and functional status of the two groups after treatment were evaluated. At the same time, the survival rates of the two groups were observed and statistically analyzed within 3 years. Results: The average PS score of the observation group was lower than that of the control group (P <0.05), and the average KPS score was higher than that of the control group (P <0.05). The 3-year survival rate was 58.33% in the observation group and 37.5% in the control group. The survival rate in the observation group within 3 years was higher than that in the control group (P <0.05). Conclusion: Compared with simple laparoscopic surgery, neoadjuvant chemotherapy combined with surgical treatment of colorectal cancer is more significant clinical efficacy, can effectively improve the patient’s physical condition, improve functional status, and improve the survival rate of patients within 3 years, it is worth clinical Promotion and application.