论文部分内容阅读
目的：测量正常成人及颞叶癫痫病人海马体积，讨论其在颞叶癫痫（ＴＬＥ）致痫灶定侧中价值。方法：本组包括５２例正常成人和２６例颞叶癫痫病人，后者有２２例为顽固性癫痫。均作垂直于海马轴的冠状位ＳＥ序列Ｔ１加权像、ＴｕｒｂｏＳＥＴ２加权像，测量颞叶、海马体积和颞角、环池宽度，肉眼观察Ｔ２加权像海马信号强度改变。采用海马体积绝对值对ＴＬＥ定侧。结果：获取了正常成人海马体积。２２例ＴＬＥ海马体积缩小，其中３例为双侧性；６例海马硬化经手术、病理证实，１例体积正常且致痫灶位于海马周围者海马硬化轻。３例ＴＬＥ病人同侧前颞叶萎缩；部分ＴＬＥ病侧颞角、环池宽度增加；萎缩明显的海马Ｔ２加权像信号弥漫性增高。结论：海马体积缩小、Ｔ２加权像信号弥漫性增高是海马硬化萎缩的直接征象，与病变严重程度、致痫灶在颞叶的部位有关。前颞叶萎缩和颞角、环池增宽是海马硬化的辅助征象
Objective: To measure the volume of hippocampus in normal adults and patients with temporal lobe epilepsy and to discuss its value in determining the epileptic side of temporal lobe epilepsy (TLE). Methods: This group includes 52 normal adults and 26 patients with temporal lobe epilepsy, the latter 22 patients with refractory epilepsy. The coronal SE sequence T1 weighted images and TurboSET2 weighted images perpendicular to the hippocampus axis were used to measure the temporal lobe and hippocampal volume and temporal angle and the width of the circumferential pool. The intensity of T2 weighted image hippocampal signal intensity was observed. The absolute value of hippocampal volume TLE set side. Results: Normal adult hippocampal volume was obtained. 22 cases of TLE hippocampal volume was reduced, of which 3 cases were bilateral; 6 cases of hippocampal sclerosis by surgery, confirmed by pathology, 1 case of normal volume and epileptogenic focus in the hippocampus around the hippocampus sclerosis. 3 cases of TLE patients ipsilateral anterior temporal lobe atrophy; part of the TLE lateral horn, annular pool width increased; atrophy obviously hippocampal T2 weighted image signal diffusely increased. Conclusion: The volume of hippocampus and the diffuse increase of T2 weighted image are the direct signs of hippocampal sclerosis and atrophy, which are related to the severity of the lesion and the location of the focal lesion in the temporal lobe. Anterior temporal lobe atrophy and the temporal horn, ring pool widening is an auxiliary sign of hippocampal sclerosis