目的　探讨结直肠癌肝转移的防治 ,对提高患者的长期生存和改善其预后具有重要意义。方法　通过手术切除有可能根治的一种实体瘤的转移性病变 ,对于多发性、无法切除的肝转移则首先选用肝动脉滴注化疗。结果　对结直肠癌肝转移的治疗 ,已从消极转为积极多途径的综合治疗 ,取得一定的效果。结论　结直肠癌肝转移是可以积极预防和治疗的。 Objective To explore the prevention and treatment of liver metastasis of colorectal cancer, which is of great significance for improving the long-term survival of patients and improving their prognosis. Methods Liver artery instillation chemotherapy was the first choice for multiple, unresectable liver metastases by surgical removal of metastatic lesions of a solid tumor that may be cured. Results The treatment of colorectal liver metastases has changed from a negative to a positive multi-modality comprehensive treatment and achieved certain results. Conclusion Liver metastasis of colorectal cancer can be actively prevented and treated.