目的　了解珠江三角洲工厂外来女工艾滋病相关知识、态度、信念、行为 (KABP) ,探索适合该人群的有效的艾滋病干预模式。方法　采用匿名问卷法对外来女工进行基线调查后开展针对该人群的艾滋病综合干预措施 ,并对干预结果进行评价。结果　工厂外来女工艾滋病知晓程度非常低 ,缺乏自我保护意识和能力 ,生殖健康状况较差 ,是艾滋病的脆弱人群。干预后 ,其对艾滋病传播途径和预防方法的知晓率显著提高 ,安全性行为率增高 ,安全套使用率增高。结论　干预模式取得明显效果 ,可在该类人群中推广。 Objective To understand AIDS-related knowledge, attitudes, beliefs and behaviors (KABP) among migrant women workers in the Pearl River Delta and to explore effective AIDS intervention models suitable for this population. Methods Anonymous questionnaires were used to conduct a baseline survey on migrant women workers to carry out HIV / AIDS comprehensive interventions for this population and to evaluate the intervention results. Results Migrant women workers at the factory had a very low level of AIDS awareness, lack of self-protection awareness and ability, and poor reproductive health, which were among the vulnerable groups of AIDS. After the intervention, its awareness of HIV transmission and prevention methods was significantly improved, the safety behavior rate increased, condom use rate increased. Conclusion The intervention model has achieved remarkable results and can be promoted among such groups.