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目的:分析研究哈萨克族受检人群肥胖与脂代谢紊乱关系。方法:2013年1月~12月在阿勒泰地区收集健康检查人群,对其一般健康指标和血液生化指标检测并统计分析。甘油三脂结果:哈萨克族除了高密度脂蛋白水平男性低于女性外,其他指标均高于女性(P<0.05)。除了男性甘油三酯水平,其他各代谢性指标均有随年龄增长而升高的趋势。受检人群中肥胖的检出率为51.1%。受检人群中高胆固醇血症、低高密度脂蛋白血症、高甘油三酯血症以及混合型高脂血症检出率分别为23%,19.3%,15.4%和7.6%,男性均高于女性P<0.05)。肥胖情况下男性和女性肥胖人群罹患高甘油三酯血症的危险分别增加了1.448倍和1.772倍,罹患高胆固醇血症的危险分别增加了2.877倍和2.561倍,罹患混合型高脂血症的危险分别增加了2.488和3.781倍,但是对低高密度脂蛋白血症的发生影响不大。结论:哈萨克族受检人群代谢性紊乱表现出性别差异和特点,尤其是该民族肥胖检出率较高,同时肥胖增加了罹患脂代谢紊乱的危险性,推测可能与该民族高蛋白和高脂膳食结构有关,因此改变生活方式和膳食习惯及早控制代谢性紊乱,以及由其引发的心脑血管疾病发生具有重要的意义。
Objective: To analyze the relationship between obesity and dyslipidemia in Kazak subjects. Methods: From January to December 2013, health checkups were collected from Altay area and their general health and blood biochemical indexes were detected and statistically analyzed. Triglyceride results: In addition to high-density lipoprotein in Kazak male lower than women, other indicators were higher than the female (P <0.05). In addition to male triglyceride levels, the other metabolic indicators are increasing with age. The detection rate of obesity in the subjects was 51.1%. The detection rate of hypercholesterolemia, low-density lipoproteinemia, hypertriglyceridemia, and mixed hyperlipidemia in the subjects was 23%, 19.3%, 15.4% and 7.6%, respectively, in males Female P <0.05). The prevalence of hypertriglyceridemia in obese men and women in obesity increased by 1.448 and 1.772, respectively, and the risk of developing hypercholesterolemia increased by 2.877 and 2.561, respectively, with mixed hyperlipidemia Risk increased by 2.488 and 3.781 times, respectively, but little effect on the occurrence of low-density lipoproteinemia. Conclusion: The metabolic disorders of Kazakh subjects showed gender differences and characteristics, especially the higher prevalence of obesity in obese people and the increased risk of dyslipidemia caused by obesity. It is presumed that this might be related to the national high protein and high fat Dietary structure, so changing lifestyle and dietary habits as early as possible to control metabolic disorders, and the cardiovascular and cerebrovascular diseases triggered by it is of great significance.