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目的:观察中西医结合治疗肝硬化顽固性腹水的临床疗效及对肾血流动力学的影响。方法:将52例肝硬化顽固性腹水患者随机分为两组各26例。对照组给予西医常规治疗,治疗组在对照组治疗基础上外用甘玉消胀散贴敷神阙穴,治疗30d后观察比较两组临床疗效及肾血流动力学的变化。结果:总有效率治疗组为84.62%,对照组为57.69%,两组比较,差异有统计学意义(P<0.01)。两组体质量、腹围治疗前后组内比较及治疗后组间比较,差异均有统计学意义(P<0.01,P<0.05)。两组肝功能治疗前后组内比较,差异均有统计学意义(P<0.05,P<0.01)。两组在改善肾血流动力学方面治疗前后组内比较及治疗后组间比较,差异均有统计学意义(P<0.05)。结论:甘玉消胀散穴位贴敷联合西医基础治疗肝硬化顽固性腹水能提高临床疗效,并对患者肾血流动力学有明显改善作用。
Objective: To observe the clinical efficacy of traditional Chinese and western medicine in the treatment of refractory ascites due to liver cirrhosis and its effect on renal hemodynamics. Methods: 52 patients with cirrhosis and refractory ascites were randomly divided into two groups of 26 cases. The control group was given routine treatment of Western medicine. The treatment group was treated with external control Ganquexiaozhang on the basis of the control group. After treatment for 30 days, the clinical curative effect and renal hemodynamics were observed and compared. Results: The total effective rate was 84.62% in the treatment group and 57.69% in the control group. There was significant difference between the two groups (P <0.01). The body mass of the two groups before and after treatment of abdominal circumference were compared and after treatment, the differences were statistically significant (P <0.01, P <0.05). There was significant difference between the two groups before and after treatment of liver function (P <0.05, P <0.01). The improvement of renal hemodynamics in both groups before and after treatment compared with the treatment group after treatment, the difference was statistically significant (P <0.05). Conclusion: Ganyu Xiaoyaosan acupoint sticking combined with Western medicine treatment of cirrhosis and refractory ascites can improve the clinical curative effect, and improve the renal hemodynamics significantly.