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目的:探讨帕罗西汀治疗2型糖尿病并抑郁患者的方法及其疗效。方法:将2010年3月～2012年11月我科收入的103例糖尿病并抑郁患者随机分为对照组、治疗组,均给予糖尿病常规治疗,治疗组在此基础上加服帕罗西汀,记录并作回顾性分析。结果:治疗前2组HADM评分、FPG、2hPG及HbA1c数值无显著性差异,而治疗后治疗组均低于对照组且差异具有统计学意义(P<0.05)。结论:2型糖尿病并抑郁患者在常规治疗基础上加用帕罗西汀疗效确切,值得进一步推广应用。
Objective: To explore the method and efficacy of paroxetine in patients with type 2 diabetes mellitus and depression. Methods: From March 2010 to November 2012, 103 patients with diabetes mellitus and depression in our department were randomly divided into control group and treatment group. All patients in the treatment group were given routine treatment of diabetes. On the basis of this, the treatment group received paroxetine, For retrospective analysis. Results: There was no significant difference in HADM score, FPG, 2hPG and HbA1c between the two groups before treatment, but the difference between the two groups after treatment was lower than that of the control group (P <0.05). Conclusion: Patients with type 2 diabetes mellitus and depression are effective in the treatment of paroxetine based on routine treatment, which is worth further promotion and application.