论文部分内容阅读
目的：探讨血清血管紧张素转换酶（ａｎｇｉｏｔｅｎｓｉｎｃｏｎｖｅｒｔｉｎｇ ｅｎｚｙｍｅ ， Ａ Ｃ Ｅ） 活性变化对肺部疾病诊断的价值。方法：采用紫外比色法检测血清 Ａ Ｃ Ｅ 活性。结果：肺炎及肺结核患者血清 Ａ Ｃ Ｅ 活性分别为（３５１ ±９３） Ｕ／ Ｌ 和（３９６ ±１０２） Ｕ／ Ｌ，与对照组（３７４ ±９４） Ｕ／ Ｌ 相比均无显著性差异（ Ｐ＞ ００５） ，３６例肺癌患者血清 Ａ Ｃ Ｅ 活性（２９２ ±９６） Ｕ／ Ｌ，明显低于肺炎、肺结核患者及对照组；６７ 例肺结节病患者血清 Ａ Ｃ Ｅ 活性（６５８ ±１３６） Ｕ／ Ｌ，明显高于对照组、肺癌、肺炎及肺结核组（ Ｐ＜ ０００１） 。结论：血清 Ａ Ｃ Ｅ 活性测定可作为诊断肺癌或肺结节病的重要指标，有助于肺癌、肺结节病和肺结核、肺炎的鉴别诊断。
Objective: To investigate the value of serum angiotensinconverting enzyme (ACE) activity in the diagnosis of pulmonary diseases. Methods: Serum A C E activity was detected by UV colorimetry. Results: Serum ACE levels in patients with pneumonia and pulmonary tuberculosis were (351 ± 93) U / L and (396 ± 102) U / L respectively, which were significantly higher than those in the control group (374 ± 94 ) U / L (P> 005). The serum A C E activity (292 ± 96) U / L in 36 patients with lung cancer was significantly lower than that in patients with pneumonia, pulmonary tuberculosis and control Group. The serum A C E activity (658 ± 136) U / L in 67 patients with pulmonary sarcoidosis was significantly higher than that in control group, lung cancer, pneumonia and pulmonary tuberculosis (P <0001). Conclusion: The determination of serum ACE activity can be used as an important index in the diagnosis of lung cancer or pulmonary sarcoidosis and contribute to the differential diagnosis of lung cancer, pulmonary sarcoidosis and tuberculosis and pneumonia.