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目的分析环丝氨酸治疗耐多药肺结核的不良反应。方法选取我院就诊的耐多药肺结核患者102例,随机分为观察组(耐药结核病化学治疗指南治疗)和对照组(常规治疗)各51例。对比两组不良反应。结果观察组病灶吸收率96.15%显著高于对照组68.00%(P<0.05)。观察组不良反应发生率13.73%显著少于对照组25.49%(P<0.05)。结论环丝氨酸治疗耐多药肺结核疗效确切,不良反应发生率较低,值得临床推广。
Objective To analyze the adverse reactions of cycloserine in the treatment of multidrug-resistant pulmonary tuberculosis. Methods A total of 102 MDR-TB patients treated in our hospital were randomly divided into observation group (treatment with drug-resistant tuberculosis) and control group (conventional treatment) with 51 cases in each group. Compare two groups of adverse reactions. Results The absorption rate of lesions in observation group was significantly higher than that in control group (96.15%, 68.00%, P <0.05). The incidence of adverse reactions in observation group was significantly lower than that in control group (13.73% vs 25.49%, P <0.05). Conclusion Cyclosporine treatment of multidrug-resistant pulmonary tuberculosis curative effect is exact, the incidence of adverse reactions is low, worthy of clinical promotion.