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华法林为是一种合成的香豆素类口服抗凝药物,主要用于预防凝血和治疗血栓性疾病,其结构与维生素K相似,作用机理是在体内竞争性抑制维生素K依赖性凝血因子的合成而发挥抗凝血的作用。临床应用广泛,在体内可受到很多药物的影响,出现相互作用,本文旨在探讨华法林与其他药物的相互作用,为临床安全用药提供参考依据。
Warfarin is a synthetic coumarin oral anticoagulant, which is mainly used to prevent coagulation and to treat thrombotic diseases. Its structure is similar to that of vitamin K, and its mechanism of action is to inhibit the vitamin K-dependent coagulation factor The synthesis and play the role of anti-clotting. Clinical application of a wide range of drugs in the body can be affected by the interaction, the interaction of this paper aims to investigate the interaction of warfarin and other drugs for clinical drug use to provide a reference.