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选用成年大鼠切除卵巢，所形成的骨质疏松症动物模型，研究骨质疏松症的病理机制和防治药物的选择。应用电子显微镜观察到骨松质亚细胞结构发生了破骨细胞增生活跃，有溶骨现象
Select the ovariectomized adult rats, the formation of animal models of osteoporosis, the pathophysiology of osteoporosis and prevention and treatment of drug selection. Electron microscopy showed osteoclastogenesis in osteoclast subcellular structures with osteolytic activity