2003年10月24日,国家药监局出台289号文件《关于加强零售药店抗菌药物销售监管促进合理用药的通知》,对抗菌药物的销售做出限制。一纸“限售令”横空出世,生产厂家和零售药店的反应千差万别:有的觉得前途一片黑暗,有的开始进行大幅调整,有的认为影响虽有但尚不足为虑,而有的则 On October 24, 2003, SFDA issued Circular No. 289 on Strengthening the Supervision and Administration of Marketing of Antibiotics in Retail Pharmacies to Promote the Rational Use of Drugs, which sets limits on sales of antibacterial drugs. A paper “Restriction Order” was born, the reaction of manufacturers and retail pharmacies vary widely: Some feel the future is dark, and some began to make substantial adjustments, while others think that the impact of but not enough consideration, while others are