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研究了诺氟沙星离子选择电极的制备方法。将该电极应用于诺氟沙星胶囊制剂的测定。在NaAc-HAc(pH4.0)底液中,电极响应的线性范围为1.0×10-4~1.0×10-2mol·L-1,七次测定的标示量百分含量的平均值为94%,与药典法测定结果基本一致,相对标准偏差为1.0%。
The preparation of norfloxacin ion-selective electrode was studied. The electrode was applied to the determination of norfloxacin capsules. The linear range of electrode response in NaAc-HAc (pH4.0) was 1.0 × 10-4 ~ 1.0 × 10-2mol·L-1. The average of the labeled amount of seven determinations The value of 94%, and the results of the determination of the pharmacological method is basically the same, the relative standard deviation of 1.0%.