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[目的]了解儿童重症结核致病的影响因素。[方法]采取以社区为基础的病例对照流行病学研究方法,筛选出儿童结脑等重症结核病例,根据病例的年龄、性别、来源地信息按1:3比例选取合适的对照,填写问卷调查表。采用Epi Info软件对资料进行卡方检验、单因素条件Logistic回归分析。[结果]纳入42例病例,126名对照。两组间家庭人口、家庭年总收入、家庭总居住面积、住宅状况、慢性疾病史,差异无统计学意义。肺结核病接触史和接触程度、与肺结核病人的关系、肺结核病史与儿童结脑等重症结核发病有统计学显著性关联。[结论家庭人口总数、家庭年总收入、家庭总居住面积、居住地状况、住宅状况、有无慢性病史等因素与儿童结脑等重症结核的发病无关。肺结核病人接触史、接触密切程度是儿童结脑等重症结核的影响因素。
[Objective] To understand the influencing factors of severe tuberculosis in children. [Methods] A community-based case-control epidemiological study was conducted to screen out children with tuberculosis of tuberculosis and other severe tuberculosis cases. According to the age, sex and origin of the cases, the appropriate control was selected according to the ratio of 1: 3, and questionnaires were filled in table. Epi Info software was used to carry out chi-square test and single factor conditional logistic regression analysis. [Results] 42 cases and 126 controls were included. There was no significant difference between the two groups in family size, total annual family income, total family living area, housing status, and chronic disease history. Tuberculosis exposure history and exposure, the relationship with tuberculosis patients, the history of tuberculosis and children with tuberculosis and other severe tuberculosis incidence was statistically significant correlation. [Conclusion The total number of family members, total annual household income, total family living area, living conditions, residential conditions, with or without chronic history and other factors have nothing to do with the incidence of tuberculosis and other severe tuberculosis in children. Tuberculosis patients contact history, close contact with children tuberculosis and other severe tuberculosis affecting factors.