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高级别前列腺癌在形态学上与高级别尿路上皮癌可出现重叠,但二者在治疗上有本质的差别。关于高级别腺泡型前列腺癌出现假乳头状结构文献中尚未见报道。作者对过去7年间遇到的7例酷似尿路上皮癌假乳头状结构的前列腺癌进行报道。7例中有3例最初误诊为尿路上皮癌,5例累及前列腺部尿道,6例累及膀胱。肿瘤细胞主要呈巢状及片状生长,局部区域癌细胞围绕中心血管形成乳头状结构。大多数病例肿瘤细胞核较一致,核仁明显,1例伴有多形性巨细胞,另1例伴有肉瘤样特征。2例伴有坏死。1例合并膀胱低级别
High-grade prostate cancer may overlap morphologically with high-grade urothelial carcinoma, but there is an essential difference in treatment. There have been no reports on the occurrence of pseudopapillary structures in high-grade acinar-type prostate cancer. The authors report on the seven cases of prostate cancer that resembled urothelium pseudopapillary structures encountered in the past seven years. Three of the seven cases were initially misdiagnosed as urothelial carcinoma, five involving the prostatic urethra and six involving the bladder. Tumor cells mainly nest-like and sheet-like growth, local area of the cancer cells around the formation of papillary structures. In most cases, the nuclei of tumor cells were more consistent, the nucleoli were obvious, one was accompanied by pleomorphic giant cells and the other was accompanied by sarcomatoid features. 2 cases with necrosis. One case had bladder low grade