5-氨基吡唑类化合物,经重氮化后,在铜粉存在下,可高收率地生成相应的5-H-吡唑衍生物。研究证明,铜粉作为还原剂直接参与了反应。为考察反应的适用范围,选用含不同取代基的5氨基吡唑衍生物进行研究,结果表明,它们均能被还原,高收率地生成相应的还原产物。该方法操作简便、反应条件温和、时间短、产物易分离纯化。 5-aminopyrazole compounds, after diazotization, in the presence of copper powder, the corresponding 5-H-pyrazole derivatives can be formed with high yield. Studies have shown that copper powder as a reductant directly involved in the reaction. In order to investigate the applicable range of the reaction, 5-aminopyrazole derivatives with different substituents were selected and studied. The results showed that all of them could be reduced to produce corresponding reduction products with high yield. The method is simple, the reaction conditions are mild, the time is short, and the product is easily separated and purified.