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免疫球蛋白超家族的跨膜蛋白(CD147/basigin)的主要作用是通过诱导基质金属蛋白酶(matrix metalloproteinase,MMP)的产生来促进基质的降解,在多种肿瘤中高表达,也参与多种炎症性疾病的发生发展。本文就CD147与炎症性疾病关系的研究进展做一综述。
The main role of the immunoglobulin superfamily of transmembrane proteins (CD147 / basigin) is to promote matrix degradation by inducing the production of matrix metalloproteinase (MMP), which is highly expressed in many tumors and is also involved in various inflammatory The development of the disease. This article reviews the progress of the research on the relationship between CD147 and inflammatory diseases.