Dobias等报道抗寄生虫药物甲硝哒唑(灭滴灵,Metronidazale)的致突变性可用人或实验动物血液中代谢物出现的突变性评价。在复方苯酚糊剂的组分中,阿的平对Ames法所用的试验菌TA 1537显示致突变性,有时它还被用作TA 1537的阳性对照[浙江医科大学农药研究室:Ames试验评价,内部资料]。故我们采用动物给药后测其血液的突变性以探讨绝育药物复方苯酚糊剂对人产生致突变的可能性。 Dobias et al. Reported that the mutagenicity of the antiparasite metronidazole (metronidazale) can be assessed by the presence of mutations in the blood or metabolites of human or laboratory animals. In the components of the compound phenol paste, albitux showed mutagenicity against the test bacteria TA 1537 used in the Ames method and sometimes it was also used as a positive control for TA 1537 [Pesticide Research Laboratory, Zhejiang Medical University: Ames test evaluation, Internal Information]. Therefore, we test the mutation of the blood after the animal is administered to investigate the possibility of mutagenicity of the phenolic compound phenol compound for sterilization.