巨噬细胞(Macrophage简称MΦ)早已超出了“清道夫细胞”这一概念。近年来证实MΦ在机体内具有多种免疫功能,特别是激活的MΦ远比未激活的MΦ更能发挥免疫作用。本文仅对MΦ的激活及其在肿瘤免疫中的作用作如下介绍。一、MΦ的激活及激活物根据形态学观察及生化测定,加入激活物质后可使MΦ在形态,代谢上发生明显的变化。形态上:细胞体积增大,向外扩展能力增强;皱褶增多,膜的活性增强,伪足 The macrophage (Macrophage referred to as MΦ) has long surpassed the concept of “Scavenger cells.” In recent years, it has been confirmed that MΦ has multiple immune functions in the body, and in particular, activated MΦ is far more effective than inactivated MΦ. This article only describes the activation of MΦ and its role in tumor immunity as follows. I. Activation and activation of MΦ According to morphological observations and biochemical assays, the addition of activating substances can cause significant changes in the morphology and metabolism of MΦ. Morphologically: the volume of the cells increases and the ability to expand outwards increases; wrinkles increase, membrane activity increases, pseudopodia