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食道静脉曲张破裂出血,是影响肝硬化病人预后的严重病理状态。目前临床上常用的治疗方法有:①外科手术;②三腔管压迫止血;③内窥镜硬化疗法;④经皮经肝门静脉栓塞术;⑤药物疗法:β-阻滞剂、脑垂体后叶素、生长抑素等。其中尤以压迫止血和药物疗法简便易行,为此已广泛普及。药物疗法中,最近又以生长抑素受到人们的重视。该药是由垂体后叶等分泌,是由14个氨基酸构成的多肽。已知其主要药理作用是抑制生长素、胃泌素、垂体前叶激素及各种消化道激素的分泌。此外尚有许多关于其对中枢神经系统、胰腺内分泌系统、肾
Esophageal variceal bleeding is a serious pathological condition that affects the prognosis of patients with cirrhosis. At present, the commonly used clinical treatment methods are: ① surgery; ② three-lumen tube hemostasis; ③ endoscopic sclerotherapy; ④ percutaneous transhepatic portal vein embolization; ⑤ drug therapy: β-blockers, pituitary gland Su, somatostatin and so on. In particular, oppression and hemostasis and drug therapy is simple and convenient, which has been widely used. In drug therapy, somatostatin has recently attracted people’s attention. The drug is secreted by the posterior pituitary and is composed of 14 amino acids of the polypeptide. Its main pharmacological effects are known to inhibit the secretion of auxin, gastrin, anterior pituitary hormones and various gastrointestinal hormones. There are many more about its effects on the central nervous system, the pancreatic endocrine system, and the kidneys