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目的:观察乳岩方对于乳腺癌术后抑郁患者的改善情况。方法:使用Zung抑郁自评量表(SDS)对乳腺癌术后患者进行评分,选出评分≥41分者,使用信封法随机分为两组,治疗组给予乳岩方治疗3个月,对照组给予不含乳岩方中的中药服用3个月,3个月后重新评分,对症状和生活质量的改善做评价。结果:SDS总分治疗组由(45.40±1.51)分降至(33.9±1.54)分,对照组由(46.60±1.12)分降至(42.75±1.37)分,治疗组改善优于对照组(P<0.05);治疗组在抑郁、易哭、睡眠障碍、便秘、心悸、易倦、不安、绝望、易激惹等方面治疗前后比较有显著差异(P<0.05),而对照组只在心悸、易倦、绝望症状改变上有显著差异(P<0.05)。结论:乳岩方对于乳腺癌术后抑郁状况有改善作用,且无明显毒副反应。
Objective: To observe the improvement of Ruyan prescription for patients with postoperative depression of breast cancer. Methods: The postoperative patients with breast cancer were scored using the Zung Self-rating Depression Scale (SDS), and those with score ≥41 were enrolled. The patients were randomly divided into two groups by envelope method. The treatment group was treated with Yanyanfang for 3 months. The rats in the group were given the traditional Chinese medicine without milk rock for 3 months and re-scored after 3 months to evaluate the improvement of the symptoms and quality of life. Results: The score of SDS in the treatment group decreased from (45.40 ± 1.51) to (33.9 ± 1.54) points, while that in the control group decreased from (46.60 ± 1.12) to (42.75 ± 1.37) points, and the treatment group improved more than the control group <0.05). The treatment group had significant difference (P <0.05) before and after treatment in the aspects of depression, easy to cry, sleep disturbance, constipation, palpitations, tiredness, anxiety, despair and irritability. There was a significant difference in the symptoms of tiredness and desperation (P <0.05). Conclusion: RuYanFang can improve postoperative depression status of breast cancer without any obvious side effect.