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生殖免疫学的核心问题是母体对同种异体抗原(胚胎)的耐受机制。母体界面免疫细胞——NK细胞和Th细胞与生殖免疫耐受状态密切相关。近年来发现的第4类淋巴细胞——NKT细胞,在维持妊娠或诱发流产过程中起重要作用。综述NKT细胞的研究现状及其与生殖免疫的关系。
The core issue of reproductive immunology is the maternal tolerance mechanism to alloantigens (embryos). The maternal interface immune cells - NK cells and Th cells are closely related to the status of reproductive immune tolerance. In recent years, type 4 lymphocytes - NKT cells play an important role in maintaining pregnancy or inducing abortion. The current research status of NKT cells and its relationship with reproductive immunity are reviewed.