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目的探讨肛周脓肿患者的脓液细菌培养和药敏试验结果。方法选择大连大学附属新华医院2013年9月至2014年8月收治的50例肛周脓肿患者作为研究对象,对脓液进行细菌培养与药敏试验,分析结果。结果 45例细菌生长,占90.0%;15例单一细菌感染,感染率为33.3%;30例混合感染,感染率为66.7%;其对阿米卡星、亚胺培南、哌拉西林/他唑巴坦、头孢吡肟以及厄他培南等药物具有较高的敏感度;对氨苄西林、头孢唑啉以及庆大霉素具有较高的耐药率;对磺胺类复方新诺明的耐药率达50.0%,对喹诺酮类药物左氧氟沙星的耐药率为25.9%,环丙沙星的耐药率为39.7%。结论肛周脓肿感染的主要病原菌为肠杆菌科细菌,为降低病原菌耐药率,增强肛周脓肿疗效,需要合理选择应用抗菌药物。
Objective To investigate the results of bacterial culture and drug susceptibility test in patients with perianal abscess. Methods Fifty patients with perianal abscess admitted to Xinhua Hospital affiliated to Dalian University from September 2013 to August 2014 were selected as the research object. Bacterial culture and drug sensitivity test were performed on the pus. The results were analyzed. Results 45 cases of bacterial growth, accounting for 90.0%; 15 cases of single bacterial infection, the infection rate was 33.3%; 30 cases of mixed infection, the infection rate was 66.7%; its amikacin, imipenem, piperacillin / Zolbactam, cefepime and ertapenem and other drugs with high sensitivity; ampicillin, cefazolin and gentamicin have a higher resistance rate; sulfamethoxazole cotrimoxazole resistance The drug resistance rate was 50.0%. The resistance rate to quinolone levofloxacin was 25.9% and that of ciprofloxacin was 39.7%. Conclusion The main pathogen of perianal abscess infection is Enterobacteriaceae. To reduce the rate of pathogenic bacteria and enhance the efficacy of perianal abscess, antibiotics should be selected reasonably.