本研究设计并合成了丙型肝炎病毒核心区相关抗原—ＣＰ９和ＧＯＲ二段肽，介绍了固相合成肽方法及纯化过程，经鉴定在高压液相柱及ＳＤＳ－ＰＡＧＥ电泳上均一。为了制备多肽抗血清，于多肽上连接蛋白质（ＢＳＡ），并采用微量免疫方法获得了高效价免疫血清—抗ＣＰ９和抗ＧＯＲ。这在合成肽和多肽抗体的制备上具有一定意义。 This study designed and synthesized hepatitis C virus core antigen-CP9 and GOR two-segment peptide, introduced the solid-phase synthetic peptide method and purification process, identified in the high-pressure liquid column and SDS-PAGE electrophoresis homogeneous. To prepare the polypeptide antiserum, proteins (BSA) were linked to the polypeptides and high titer immune sera-anti-CP9 and anti-GOR were obtained using the microprojectile method. This is of some significance in the preparation of synthetic peptides and polypeptide antibodies.