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选择门诊和住院１５０例原发性高血压病人，将病人随机分为三组。Ａ组（单纯服用巯甲丙脯酸）５０例，巯甲丙脯酸２５毫克每日三次口服。Ｂ组（巯甲丙脯酸与硝苯地平联合用药）５０例．巯甲丙脯酸２５毫克和硝苯地平１０毫克每日三次口服。Ｃ组（单纯服硝苯地平）５０例，硝苯地平１０毫克每日三次口服。药物疗效判定按心血管病流行病学研究及人群防治工作１９７９－１９８５年规划中标准。Ａ组总有效率７８％，Ｂ组总有效率９４％，Ｃ组总有效率８５％。结果表明两药联合应用降压迅速，且有效率高，在改善左心功能，减退左室肥厚等方面有协同作用。
Select outpatient and hospitalized 150 cases of essential hypertension patients, the patients were randomly divided into three groups. Group A (pure captopril) 50 cases, captopril 25 mg orally three times daily. Group B (captopril and nifedipine combination) in 50 cases. 25 mg of captopril and 10 mg of nifedipine orally three times daily. Group C (nifedipine alone) in 50 cases, nifedipine 10 mg orally three times daily. Drug efficacy judgment by epidemiology of cardiovascular disease research and crowd prevention and control work 1979-1985 standard planning. The total effective rate in group A was 78%, the total effective rate in group B was 94%, and the total effective rate in group C was 85%. The results show that the two drugs combined with rapid antihypertensive, and high efficiency, improve left ventricular function, reduce systolic left ventricular hypertrophy and so on.