卡马西平自 196 2年始试用于抗癫痫治疗。 1970年用于治疗躁郁症 ,我们在临床工作中遇到了 3例严重皮肤过敏同时伴发热、肝功异常的病人 ,为引起足够的重视 ,将卡马西平所致严重过敏反应的临床表现报告如下。例 1:住院号 15 817,女 ,2 6岁 ,诊断 :躁郁症躁狂状态。入院后服卡马 Carbamazepine since 196 2 years ago for anti-epilepsy treatment. 1970 for the treatment of bipolar disorder, we encountered in clinical work 3 cases of severe skin allergy with fever, abnormal liver function in patients, to attract enough attention, the clinical manifestations of carbamazepine-induced severe allergic reactions as follows. Example 1: Hospitalization 15 817, Female, 26 years old, Diagnosis: Manic-depressive disorder Manic state. After admission, Kama