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作者回顾性分析了52例临床分期为IA/IAE期大细胞淋巴瘤并对治疗方法进行评估。原发于淋巴结(IA)24例;淋巴结外(IAE)28例。26例(IA10例,IAE16例)行单纯放疗,采用4或6MV直线加速器,肿瘤区局部照射,平均剂量40Gy/20次(35～42Gy),每周4次;26例综合治疗(IA13例,IAE13例)行CHOP或M-BACOP方案化疗,常规剂量3周期后休息一段时间再行肿瘤区放疗36Gy。52例中,死亡15例,存活37例,中位生存期6年。单纯放疗组复发死亡6例,生存20例,广泛复发3例。复发中位时间0.75年。综合治疗组死亡
The authors retrospectively analyzed 52 cases of clinical stage IA/IAE stage large cell lymphoma and evaluated the treatment method. There were 24 cases of primary lymph node (IA) and 28 cases of extra-lymph node (IAE). Twenty-six patients (IA 10 cases, IAE 16 cases) were treated with radiotherapy alone, using 4 or 6 MV linear accelerators, localized irradiation in the tumor area, average dose 40 Gy/20 times (35-42 Gy), 4 times per week; 26 cases of comprehensive treatment (IA 13 cases, 13 cases of IAE were treated with chemotherapy with CHOP or M-BACOP regimen. After a period of 3 cycles of regular doses, the patients received a rest period of 36 Gy after radiotherapy for a period of time. Of the 52 patients, 15 died and 37 survived. The median survival period was 6 years. In the radiotherapy alone group, 6 patients relapsed, 20 survived, and 3 recurred. The median time to recurrence was 0.75 years. Comprehensive treatment group died