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目的:观察参松养心胶囊联合胺碘酮对慢性心力衰竭伴室早患者生活质量的影响。方法:选择64例慢性心力衰竭伴室早患者,随机分为2组,在强心、利尿及血管扩张药治疗的基础上,治疗组服用参松养心胶囊和胺碘酮,对照组服用胺碘酮。观察治疗前后的临床疗效、左室射血分数和明尼苏达心衰量表评分的变化。结果:总有效率治疗组为87.5%,对照组为56.3%,2组比较,差异有显著性意义(P<0.05)。2组治疗前的左室射血分数比较,差异无显著性意义(P>0.05);治疗后2组均有提高,与治疗前比较,差异有显著性或非常显著性意义(P<0.05,P<0.01),但治疗组更加明显(P<0.01)。2组治疗前明尼苏达心衰量表评分比较,差异无显著性意义(P>0.05);治疗后2组均有下降,与治疗前比较,差异有显著性或非常显著性意义(P<0.05,P<0.01),但治疗组更加明显(P<0.01)。结论:参松养心胶囊联合胺碘酮治疗慢性心力衰竭伴室早患者的疗效优于单用胺碘酮,并可明显改善患者的心功能和提高生活质量。
Objective: To observe the effect of Shensong Yangxin Capsule combined with amiodarone on quality of life in patients with chronic heart failure and premature ventricular failure. Methods: Sixty-four patients with chronic heart failure accompanied by ventricular arrhythmia were randomly divided into two groups. On the basis of the treatment of cardioplegia, diuretic and vasodilator, the patients in the treatment group took Shensongyangxin Capsule and amiodarone, while the control group took amine Iodone. The changes of clinical efficacy, left ventricular ejection fraction and Minnesota Heart Failure Scale before and after treatment were observed. Results: The total effective rate was 87.5% in the treatment group and 56.3% in the control group. There was significant difference between the two groups (P <0.05). There was no significant difference in left ventricular ejection fraction between the two groups before treatment (P> 0.05); both groups improved after treatment, with significant difference between before and after treatment (P <0.05, P <0.01), but the treatment group was more obvious (P <0.01). There was no significant difference between the two groups before treatment (P> 0.05); the scores of two groups decreased after treatment, the difference was significant or very significant (P <0.05, P <0.01), but the treatment group was more obvious (P <0.01). Conclusion: Shensong Yangxin Capsule combined with amiodarone is superior to amiodarone alone in the treatment of patients with chronic heart failure and early ventricular syndrome, and can significantly improve the patient’s cardiac function and improve quality of life.