呼吸系统疾病与免疫呼吸系统疾病的变态反应有四型:Ⅰ型与浆细胞合成的免疫球蛋白E(IgE)有关,例如支气管哮喘。肥大细胞释放组织胺、慢反应物质、嗜酸性趋化因子等,引起生物效应。嗜酸细胞的增多,是由于游离的嗜酸性趋化因子增多之故。最近认为Ⅰ型变态反应不仅与IgE有关,还可能与短程致敏的亲自身细胞性IgG(Short term Sensitizing homocytotropic IgG)有 There are four types of allergy to respiratory diseases and immune-respiratory diseases: Type I is associated with immunoglobulin E (IgE) synthesized by plasma cells, such as bronchial asthma. Mast cells release histamine, slow response substances, eosinophilic chemokines, causing biological effects. Eosinophilia is due to an increase in free eosinophils. Recently, it is considered that type I allergy is not only related to IgE, but also to short-term sensitized human homologous IgG