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目的探讨蝮蛇抗栓酶合剂对术后腹腔粘连及粘连性肠梗阻的预防作用 .方法采用两种腹腔粘连的动物模型 ,分别将 6 0只大白鼠和 40只大白兔各均分成实验组和对照组 ,观察腹腔粘连情况 ,另外将 112例粘连性肠梗阻手术病人随机分成实验组和对照组 ,随访 18个月 ,观察粘连性肠梗阻复发率 .结果在动物实验和临床应用中 ,实验组的粘连百分比均显著低于对照组 (P <0 .0 1) .结论蝮蛇抗栓酶合剂可有效地预防腹腔粘连及粘连性肠梗阻的发生 ,且副反应少
Objective To investigate the preventive effect of viper antithrombotic agents on postoperative intraperitoneal adhesions and adhesive intestinal obstruction.Methods Two kinds of peritoneal adhesion animal models were used to divide 60 rats and 40 rabbits respectively into experimental group and control group Control group, observe the situation of abdominal adhesions, in addition to 112 cases of adhesive intestinal obstruction surgery patients were randomly divided into experimental group and control group, followed up for 18 months, observed the recurrence rate of adhesive intestinal obstruction.Results In animal experiments and clinical applications, experimental group (P <0.01) .Conclusion Vitex antithrombotic agents can effectively prevent peritoneal adhesions and adhesive intestinal obstruction, and less side effects