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目的观察替吉奥联合顺铂(DDP)治疗晚期胃癌的临床疗效。方法 52例晚期胃癌患者随机分为两组,治疗组24例采用替吉奥联合顺铂治疗,对照组28例采用5-氟尿嘧啶(5-Fu)联合顺铂治疗。结果治疗组总有效率、获益率、KPS评分改善者均显著高于对照组,差异有统计学意义(P<0.05)。结论替吉奥联合顺铂对于晚期胃癌,近期疗效较好,不良反应可耐受,值得推广及进一步研究。
Objective To observe the clinical efficacy of ticlopidine combined with cisplatin (DDP) in the treatment of advanced gastric cancer. Methods Fifty-two patients with advanced gastric cancer were randomly divided into two groups: 24 in the treatment group and 20 in the control group were treated with 5-fluorouracil and cisplatin. Results The total effective rate, benefit rate and KPS score in the treatment group were significantly higher than those in the control group (P <0.05). Conclusion For the combination of cisplatin and getinib for advanced gastric cancer, the curative effect is good and the side effects are tolerable. It is worth to be popularized and further studied.