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目的分析支气管哮喘临床控制与睡眠呼吸障碍的关系。方法 84例支气管哮喘患者作为研究对象,根据ACT(哮喘控制测试)结果 ,分为未控制组(ACT≤19分)40例和控制组(ACT>19分)44例,对两组患者的肺功能指标进行对比、分析。结果控制组患者的身体质量指数(BMI)、用力肺活量在预计值中的比重(FVC)、氧减饱和指数(ODI4)、平均血氧饱和度(MSa O2)、最低血氧饱和度(LSa O2)、Sa O2<90%的时间在睡眠总时间中的比重(STI90)值与未控制组相比,差异均具有统计学意义(P<0.05)。未控制组的睡眠呼吸暂停低通气综合征(SAHS)发生率显著高于控制组,差异具有统计学意义(P<0.05)。结论支气管哮喘的临床控制情况,与夜间低氧、睡眠呼吸暂停低通气综合征SAHS、肺功能均显著相关,联合进行哮喘控制测试、夜间血氧及肺功能监测,对于全面评估病情具有重要作用。
Objective To analyze the relationship between clinical control of bronchial asthma and sleep-disordered breathing. Methods A total of 84 patients with bronchial asthma were enrolled in this study. According to ACT (asthma control test), 40 patients were divided into uncontrolled group (ACT≤19) and control group (ACT> 19) Functional indicators for comparison, analysis. Results The body mass index (BMI), FVC, ODI4, MSa O2, LSa O2 in the control group ), SaO2 <90% of total sleep time (STI90) values compared with the control group, the difference was statistically significant (P <0.05). The incidence of sleep apnea-hypopnea syndrome (SAHS) in the uncontrolled group was significantly higher than that in control group, with significant difference (P <0.05). Conclusion The clinical control of bronchial asthma is significantly correlated with nocturnal hypoxia, sleep apnea-hypopnea syndrome (SAHS) and pulmonary function. Combined with asthma control test, nighttime oxygen saturation and pulmonary function monitoring, it plays an important role in the comprehensive assessment of the disease.