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目的采用因素分析可以估算微量元素锌的需要量。通过对幼儿锌代谢平衡的测定,以所获得的数据估算幼儿的锌需要量。方法收集43例19～25月龄幼儿粪便和尿液,采用双稳定性同位素示踪方法标记同位素,分析稳定性同位素丰度,计算锌的各项代谢平衡数据。结果43例幼儿膳食摄入锌量(1.86±0.55)mg/d,锌吸收率0.35±0.12;实际吸收锌量(0.63±0.24)mg/d,肠道内源性排出锌量(0.67±0.23)mg/d。由因素分析估算得到幼儿锌的生理需要量为1.09 mg/d,锌的平均膳食需要量为3.3 mg/d。结论根据实际测得的锌代谢平衡数据,由因素分析得到的幼儿锌的生理需要量和平均膳食需要量均略高于目前美国食物和营养委员会的估计值。[临床儿科杂志,2007,25(12):1016-1019]
Objective To estimate the requirement of trace element zinc by factor analysis. Through the determination of zinc metabolism in young children, the data obtained to estimate the needs of young children zinc. Methods 43 stools and urine from 19 to 25 months old children were collected. Bistable isotope tracer method was used to label the isotopes. The stability isotope abundance was analyzed and the metabolic balance data of zinc were calculated. Results The dietary intake of zinc was (1.86 ± 0.55) mg / d in 43 children and the rate of zinc absorption was 0.35 ± 0.12. The amount of zinc actually absorbed (0.63 ± 0.24) mg / d and the amount of endogenous zinc excreted (0.67 ± 0.23) mg / d. The physiological requirement for early childhood zinc was estimated to be 1.09 mg / day by factor analysis and 3.3 mg / day for zinc. Conclusions According to the actual measured zinc metabolism balance data, the physiological requirements and average dietary requirements of young children obtained by factor analysis are slightly higher than those of the current US Food and Nutritional Council estimates. [Journal of Clinical Pediatrics, 2007,25 (12): 1016-1019]