本研究在用更生霉素建立IUGR动物模型的基础上,应用人参茎叶皂甙、丹参、舒喘灵、硫酸锌和人参蜂王浆对胎仔宫内生长迟缓(IUGR)孕鼠进行治疗。结果表明,各治疗组孕鼠妊娠第20天体重明显高于更生霉素组孕鼠(P<0.01)、IUGR胎仔的发生率明显降低(P<0.01);在胎盘组织学上,胎盘的厚度及迷路层血管和血窦成分,各治疗组不同程度地有别于更生霉素组。并对各药物治疗组IUGR进行了讨论。 In this study, the animal model of IUGR was established on the basis of dactinomycin. Ginseng stem and leaf saponins, salvia miltiorrhiza, salbutamol, zinc sulfate and ginseng royal jelly were used to treat IUGR pregnant mice. The results showed that the body weight of pregnant rats at the 20th day of pregnancy in each treatment group was significantly higher than that of the maternal mice group (P<0.01), and the incidence of IUGR fetuses was significantly lower (P<0.01). In placenta histology, the placental thickness was significantly reduced. And the labyrinth layer and sinusoidal components were different from each other in the treatment group to the dactinomycin group. The IUGR of each drug treatment group was discussed.