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目的观察手术治疗食管胃结合部癌的临床疗效及预后。方法回顾性分析本院收治的42例食管胃结合部癌患者资料,施行全胃+贲门切除17例,近端胃大部切除+远端食管切除21例,全胃切除+远端食管切除4例。结果本组40例患者行手术全切除肿瘤,切除率为95.2%,无围手术期死亡病例;术后肿瘤复发者5例,食管下端癌患者与贲门癌患者术后复发率与一年生存率比较,差异无统计学意义(P>0.05),三年生存率与五年生存率比较,贲门癌患者明显高于食管下端癌患者,结果差异有统计学意义(P<0.05)。结论食管胃结合部癌应尽可能扩大淋巴结清扫范围,可有效保证手术根治度,提高预后效果。
Objective To observe the clinical efficacy and prognosis of surgical treatment of esophagogastric junction carcinoma. Methods A retrospective analysis of 42 patients with esophageal and gastric cancer treated in our hospital was retrospectively analyzed. Seventeen cases of total stomach + cardia resection, 21 cases of proximal gastrectomy + distal esophageal resection, total gastrectomy + distal esophagectomy 4 example. Results 40 patients underwent total resection of the tumor in this group, the resection rate was 95.2%, no perioperative deaths; 5 cases of tumor recurrence after surgery, lower esophageal cancer and cardia cancer recurrence rate and one-year survival rate (P> 0.05). Compared with the five-year survival rate, the three-year survival rate was significantly higher in cardia cancer patients than in patients with lower esophageal cancer, the difference was statistically significant (P <0.05). Conclusion esophagogastric junction cancer should maximize the extent of lymph node dissection, which can effectively ensure the surgical cure and improve the prognosis.