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1976~1990年收治Ⅰ期喉癌(T1N0M0)88例,采用常规分割放疗,照射剂量为DT70Gy/7周。分析放疗效果及失败因素,总的5年生存率为72.7%;其中声门型为82.1%,声门上型为56.2%;高分化鳞癌为78.3%,低分化鳞癌为96.1%,未分化病为100%,乳头状瘤癌变为33.3%,腺癌为25%,腺鳞癌、腺样囊性疾、喉粘膜白斑癌变均为剧。在选择治疗方案时,对于病理类型属于放射敏感性差、控制率低的癌,或肿瘤为声门上型,可适当考虑首选手术切除,以达到首次治疗最大限度控制肿瘤的目的。
From 1976 to 1990, 88 cases of stage Ⅰ laryngeal cancer (T1N0M0) were treated with conventional fractionated radiotherapy at the dose of DT70Gy / 7 weeks. Analysis of radiotherapy and failure factors, the overall 5-year survival rate was 72.7%; of which the glottis was 82.1%, supraglottic 56.2%; well-differentiated squamous cell carcinoma was 78.3%, low Differentiated squamous cell carcinoma was 96.1%, undifferentiated disease was 100%, papilloma was 33.3%, adenocarcinoma was 25%, adenosquamous carcinoma, adenoid cystic disease, laryngeal mucosal leukoplakia are drama. In the choice of treatment options, the pathological type of radiation sensitivity is poor, low control rate of cancer, or supraglottic tumor, may be the first choice of surgical resection in order to achieve the first time to maximize the control of tumor purposes.