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载脂蛋白E(apoE)由299个氨基酸残基组成,分子量3420KD,是一种多功能糖蛋白,在脂类运输及调节脂蛋白和脂类代谢过程中起作用。apoE基因位于19号染色体长臂(19q13)上〔1〕,基因位点存在多态性,有3种常见的等位基因ε2、ε3、ε4,...
Apolipoprotein E (apoE) consists of 299 amino acid residues and has a molecular weight of 34.20 KD. It is a multifunctional glycoprotein that plays a role in the transport of lipids and in the regulation of lipoproteins and lipid metabolism. The apoE gene is located on the long arm of chromosome 19 (19q13) [1]. There are polymorphisms in the gene locus. There are three common alleles ε2, ε3, ε4, ...