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沃氟沙星(ofloxacin)是喹诺酮系口服抗菌药,对革兰氏阳性及阴性菌都有抗菌作用,口服后血中浓度迅速增高并移行到组织内,抗菌力强并有杀菌作用。本文介绍沃氟沙星治疗100例耳鼻喉科难治性感染的临床效果。男49例,女51例;中耳炎51例,副鼻窦炎45例,两者合并4例;轻症7例,中等症状76例,重症17例。
Ofloxacin is a quinolone oral antibacterial agent that has antibacterial activity against Gram-positive and -negative bacteria. After oral administration, ofloxacin rapidly increases in blood concentration and migrates into the tissues with strong antibacterial activity and bactericidal effect. This article describes the clinical efficacy of fertiloxacin in the treatment of 100 cases of otolaryngology refractory infections. 49 males and 51 females; otitis media 51 cases, 45 cases of sinusitis, the two merged in 4 cases; 7 cases of mild, moderate symptoms in 76 cases, severe cases in 17 cases.