Purpose: To test a new method of applying 5-Fluo-rouracil (5-FU) postoperatively developed by author Khaw. Methods: Observational series of 17 cases having guarded filtration procedure. 5-FU was administered postperatively as follows: The eye was anesthetized topically. A 30-gauge needle on a vial of Healon GV was introduced into the inferotemporal conjunctiva 5mm inferior to the limbus, and a bolus of 0.2 mL of Healon Purpose: To test a new method of applying 5-Fluo-rouracil (5-FU) postoperatively developed by author Khaw. Methods: Observational series of 17 cases with guarded filtration procedure. 5-FU was administered postperatively as follows: The eye was anesthetized A 30-gauge needle on a vial of Healon GV was introduced into the inferotemporal conjunctiva 5mm inferior to the limbus, and a bolus of 0.2 mL of Healon