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摘要目的比较2种活检方法即MR靶向活检(TB)与系统性活检(SB)的结果。材料与方法本研究为经机构审查委员会批准的多中心研究,获得了所有病人的知情同意。2009年5月—2011年1月,共纳入疑诊前列腺癌且MRI可疑异常者95例。所有病人均接受12针系统性穿刺和经直肠超声引导下的4针靶向穿刺,其中2针为可视性的(TBCOG),2针采用经直肠超声-MR融合软件(TB-FUS)引导。对SB和TB阳性的癌灶和样本质量(核心癌灶长度的平均最长值,Gleason评分)进行比较。有临床意义的癌灶定义为SB下核心癌灶长度≥3 mm或任何Gleason评分超过3分的癌灶,以及TB下任何长度的癌灶。统计分析包括t检验、配
Abstract Objective To compare the results of two biopsy methods, MR targeted biopsy (TB) and systematic biopsy (SB). Materials and Methods The study was a multicenter study approved by the Institutional Review Board and obtained the informed consent of all patients. May 2009 - January 2011, a total of 95 suspected cases of suspected prostate cancer and MRI were suspected. All patients underwent 12-needle systematic puncture and 4-needle targeted puncture guided by transrectal ultrasound with 2-needle visualization (TBCOG) and 2-needle delivery using transrectal ultrasound-MR fusion software (TB-FUS) . The SB and TB positive foci were compared with sample quality (mean longest length of core foci, Gleason score). A clinically significant foci is defined as a foci with a length of ≥3 mm in SB or any Gleason with a score of more than 3, and a foci of any length in TB. Statistical analysis including t test, with