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目的了解入伍新兵人群中百日咳IgG抗体的流行分布情况,为今后预防提供科学依据。方法采用血清流行病学调查方法,利用酶联免疫吸附试验(ELISA)技术,对北京军区近4年来自7个省市的360名入伍新兵血清进行百日咳IgG抗体检测,统计分析其阳性率。结果入伍新兵血清百日咳IgG抗体各年间无显著增高趋势,阳性率为92.16%～100.00%,平均97.50%;IgG抗体阳性率地区间差异无统计学意义,浙江省(100.00%)、山东省(100.00%)和河南省(100.00%)较高,内蒙古(92.16%)和湖北省(96.67%)较低;入伍前工作与否,抗体阳性检出率差异无统计学意义。结论入伍新兵人群中百日咳IgG抗体阳性率为92.16%～100.00%,无逐年显著增高或降低趋势,无明显地区差异。
Objective To understand the epidemic distribution of pertussis IgG antibody in recruits recruits, providing a scientific basis for future prevention. Methods Serum epidemiological investigation method was used to detect pertussis IgG in 360 recruits from 7 provinces and cities in the Beijing Military Region in the past 4 years by enzyme-linked immunosorbent assay (ELISA), and the positive rate was determined by statistical analysis. Results The seroprevalence of pertussis IgG in recruits was no significant increase in each year, the positive rate was 92.16% -100.00%, with an average of 97.50%. There was no significant difference between the positive rates of IgG antibodies in Zhejiang Province (100.00%), Shandong Province %) And Henan Province (100.00%) were higher in Inner Mongolia (92.16%) and Hubei Province (96.67%). There was no significant difference in the detection rate of antibody positive before entering the army. Conclusions The prevalence of pertussis IgG in recruits recruits from 92.16% to 100.00%, no significant increase or decrease year by year, with no obvious regional differences.