目的探讨移植治疗重症肌无力的疗效,造血重建、移植相关并发症和无事件生存情况。方法自体外周造血干细胞移植治疗2例重症肌无力患者,其中男女各1例,移植时分别为38岁及37岁,移植前都在我院神经内科诊断为重症肌无力5年,都经过免疫抑制剂冲击治疗,效果不理想,前者因合并胸腺瘤,曾行手术切除胸腺治疗,在药物维 Objective To investigate the efficacy of transplantation for myasthenia gravis, hematopoietic reconstitution, complications related to transplantation and event-free survival. Methods Two cases of myasthenia gravis were treated by autologous peripheral blood stem cell transplantation. One patient was male and one female. The patients were 38 years old and 37 years old respectively. Before the transplantation, all cases were diagnosed myasthenia gravis in our department for 5 years before immunosuppression Agent impact treatment, the effect is not satisfactory, the former due to the merger of thymoma, thymectomy had undergone surgical treatment in the drug dimension