论文部分内容阅读
本文选择20例支气管哮喘急性发作患者,用沙丁胺醇,按4μg/kg的负荷量作静脉推注。经用药前、后的肺通气功能测定比较,于用药后即刻、15min,30min,1h,2h的FEV_1均比用药前有明显的改善(P<0.001),其药效高峰时间为用药后15min左右,作用时间维持在2h以上。用药后20例患者的FEV_1比用药前均可增加≥20％,其中13例(65％)增加达≥40％。患者在用药后肺通气功能改善的同时,其胸闷,气急和咳嗽等临床症状好转,哮鸣音减少或消失。作者认为沙丁胺醇静脉注射治疗支气管哮喘急性发作患者,具有临床疗效好,起效快,药效高峰出现早等优点。
In this paper, 20 patients with acute exacerbation of bronchial asthma were selected and treated with salbutamol at a dose of 4 μg / kg for intravenous injection. The pulmonary function tests before and after treatment showed that the FEV_1 at 15 min, 30 min, 1 h and 2 h after operation was significantly improved (P <0.001) compared with that before treatment, and the peak time was about 15 min after administration , The role of time maintained at 2h above. After treatment, FEV_1 in 20 patients increased more than 20% before the treatment, of which 13 cases (65%) increased up to 40%. Patients with pulmonary ventilation improved after treatment at the same time, the chest tightness, shortness of breath and cough and other clinical symptoms improved, wheeze reduction or disappearance. The authors believe that salbutamol intravenous treatment of patients with acute exacerbation of bronchial asthma, with good clinical efficacy, rapid onset, peak efficacy appeared early and other advantages.