论文部分内容阅读
当异物进入人或动物的血液中,身体内会产生抵抗异物的物质,医学界把前者称为抗原,后者称为抗体。负责产生抗体是B淋巴细胞。每一种B淋巴细胞只能产生针对某种抗原决定簇的一种抗体,这种抗体理化性质均一,特异性相同,由于是一个细胞克隆所产生的,故称之为单克隆抗体。在当前医药常规工作中,我们所用的抗体是由多种抗原决定簇刺激机体所产生的,所以是多克隆抗体。这种抗体由于不纯净,可以和多种抗原发生反应,即非特异性结合,这往往严重地影响了诊断和治疗。因此,多年来,医学
When foreign matter enters into the blood of humans or animals, substances in the body that are resistant to foreign matter are produced. The medical community calls the former the antigen and the latter the antibody. The responsible for producing antibodies is B lymphocytes. Each type of B-lymphocyte can only produce an antibody against an antigenic determinant. This antibody has a uniform physicochemical property and the same specificity. Since it is a cell clone, it is called a monoclonal antibody. In the current routine medical work, the antibodies we use are produced by a variety of antigenic determinants to stimulate the body, so it is a polyclonal antibody. Because of the impure nature of this antibody, it can react with multiple antigens, ie non-specific binding, which often seriously affects the diagnosis and treatment. So, over the years, medicine