地高辛是临床治疗心衰最常用的一种强心甙口服药,也是内科医生的“手术刀”。其治疗量和中毒量很接近,个体差异较大,血药安全范围狭窄,极易发生中毒危险(此药血药浓度过高时,可发生与心脏病本身症状很难区别的心律失常),是临床医生最难掌握的药物之一。一般情况下,其中毒量是治疗量的1.6倍,两者十分接近;而中毒的 Digoxin is the most commonly used clinical treatment of heart failure, a cardiac glycoside oral medication, is also a physician’s “scalpel.” The amount of treatment and the amount of poisoning is very close, the larger individual differences in the narrow range of blood drug safety, high risk of poisoning (the drug is too high plasma concentration, heart disease itself can occur very difficult to distinguish the symptoms of arrhythmias) One of the most difficult drugs for clinicians. Under normal circumstances, the dose is 1.6 times the amount of treatment, the two are very close; and poisoning